Article
RNA tertiary interactions in the large ribosomal subunit: the A-minor motif.
Proceedings of the National Academy of Sciences of the United States of America - 24 Apr 2001
Nissen P, Ippolito J A, Ban N, Moore P B, Steitz T A
Abstract excerpt
Analysis of the 2.4-A resolution crystal structure of the large ribosomal subunit from Haloarcula marismortui reveals the existence of an abundant and ubiquitous structural motif that stabilizes RNA tertiary and quaternary structures. This motif is termed the A-minor motif, because it involves the insertion of the smooth, minor groove edges of adenines into the minor groove of neighboring helices, preferentially...
Topics
- Adenosine
- Base Pairing
- Binding Sites
- Conserved Sequence
- Haloarcula marismortui
- Hydrogen Bonding
- Models, Molecular
- Mutation
- Nucleic Acid Conformation
- Protein Subunits
- RNA Stability
- RNA, Archaeal
- RNA, Ribosomal, 23S
- RNA, Ribosomal, 5S