Article
A molecular map of chloroquine resistance in Mali.
FEMS immunology and medical microbiology - 1 Feb 2010
Djimde Abdoulaye A, Barger Breanna, Kone Aminatou, Beavogui Abdoul H, Tekete Mamadou, Fofana Bakary, Dara Antoine, Maiga Hamma, Dembele Demba, Toure Sekou, Dama Souleymane, Ouologuem Dinkorma, Sangare Cheick Papa Oumar, Dolo Amagana, Sogoba Nofomo, Nimaga Karamoko, Kone Yacouba, Doumbo Ogobara K
Abstract excerpt
Plasmodium falciparum chloroquine resistance (CQR) transporter point mutation (PfCRT 76T) is known to be the key determinant of CQR. Molecular detection of PfCRT 76T in field samples may be used for the surveillance of CQR in malaria-endemic countries. The genotype-resistance index (GRI), which i...
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