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Article

Loss of G2/M arrest correlates with radiosensitization in two human sarcoma cell lines with mutant p53.

International journal of cancer - 20 Apr 2001

Bache M, Pigorsch S, Dunst J, Würl P, Meye A, Bartel F, Schmidt H, Rath F W, Taubert H

Abstract excerpt

We have examined the modulation of radiosensitivity by using caffeine in two human sarcoma cell lines both with a p53 mutation (US8-93 and LMS6-93). In both cell lines a strong irradiation-induced G2/M arrest was coupled with a low rate of apoptosis. Incubation with caffeine resulted in a low per...

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Identifiers

PMID: 11291094
DOI: 10.1002/ijc.1002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11291094-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Loss of G2/M arrest correlates with radiosensitization in two human sarcoma cell lines with mutant p53.PMID 11291094Read ↗

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