Article
Bifunctional transcriptional properties of YY1 in regulating muscle actin and c-myc gene expression during myogenesis.
Oncogene - 1 Apr 1994
Lee T C, Zhang Y, Schwartz R J
Abstract excerpt
Oncogene expression is generally incompatible with terminal cell differentiation as in myogenesis. We present evidence that this incompatibility can be caused in part by the dual activity of a Kruppel-related zinc finger, YY1 (formerly F-ACT1), in differentially regulating oncogene and muscle-spe...
Topics
- Actins
- Animals
- Cell Differentiation
- Cell Division
- Cells, Cultured
- Chick Embryo
- DNA-Binding Proteins
- Erythroid-Specific DNA-Binding Factors
- Gene Expression Regulation
- Genes, myc
- Muscles
- Mutation
- Repressor Proteins
- Trans-Activators
- Transcription Factors
- Transcriptional Activation
- YY1 Transcription Factor
- Zinc Fingers