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Article

High levels of patched gene mutations in basal-cell carcinomas from patients with xeroderma pigmentosum.

Proceedings of the National Academy of Sciences of the United States of America - 27 Apr 1999

Bodak N, Queille S, Avril M F, Bouadjar B, Drougard C, Sarasin A, Daya-Grosjean L

Abstract excerpt

Recently, hptc, a human gene homologous to the Drosophila segment polarity gene patched (ptc), has been implicated in the nevoid basal-cell carcinoma (BCC) syndrome, and somatic mutations of hptc also have been found in sporadic BCCs, the most frequent cancers found in the white population. We ha...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10220428
DOI: 10.1073/pnas.96.9.5117
PMCID: PMC21826

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10220428-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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