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The RUNX2 Cistrome in Osteoblasts

25 Apr 2014

Abstract excerpt

RUNX2 is a transcription factor that is first expressed in early osteoblast-lineage cells and represents a primary determinant of osteoblastogenesis. While numerous target genes are regulated by RUNX2, little is known of sites on the genome occupied by RUNX2 or of the gene networks that are controlled by these sites. To explore this, we conducted a genome-wide analysis of the RUNX2 cistrome in both...

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PMID: 24764292
DOI: 10.1074/jbc.m114.552216

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