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Article

Dual influence of disease and increased load on diaphragm muscle in heart failure.

Journal of molecular and cellular cardiology - 1 Apr 2001

De Sousa E, Veksler V, Bigard X, Mateo P, Serrurier B, Ventura-Clapier R

Abstract excerpt

We have recently shown that mitochondrial function and energy metabolism are altered in the myocardium as well as in slow and fast locomotor muscles of rats subjected to prolonged congestive heart failure (CHF) suggesting a generalized metabolic myopathy in heart failure. Here, we investigate whether the diaphragm of CHF animals, which experiences both increased work and the general systemic influence of heart...

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Identifiers

PMID: 11273723
DOI: 10.1006/jmcc.2000.1336

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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