Article
Effects of chronic AICAR administration on the metabolic and contractile phenotypes of rat slow- and fast-twitch skeletal muscles.
Canadian journal of physiology and pharmacology - 1 Nov 2003
Bamford Jeremy A, Lopaschuk Gary D, MacLean Ian M, Reinhart Marcia L, Dixon Walter T, Putman Charles T
Abstract excerpt
The present study examined the effects of chronic activation of 5'-AMP-activated protein kinase (AMPK) on the oxidative capacity and myosin heavy chain (MHC) based fibre phenotype of rodent fast- and slow-twitch muscles. Sprague-Dawley rats received daily injections for 4 weeks of the known AMPK...
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