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Article

Compensatory responses in mice carrying a null mutation for Ins1 or Ins2.

Diabetes - 1 Feb 2001

Leroux L, Desbois P, Lamotte L, Duvillié B, Cordonnier N, Jackerott M, Jami J, Bucchini D, Joshi R L

Abstract excerpt

Intrauterine growth retardation and postnatal acute diabetes result from insulin deficiency in double homozygous null mutants for Ins1 and Ins2 (Duvillié B, et al., Proc. Natl. Acad. Sci. USA 94:5137-5140, 1997). The characterization of single homozygous null mutants for Ins1 or Ins2 is described here. Neither kind of mutant mice was diabetic. Immunocytochemical analysis of the islets showed normal distribution...

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Source

Identifiers

PMID: 11272179
DOI: 10.2337/diabetes.50.2007.s150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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