Article
Mitochondrial DNA ligase function in Saccharomyces cerevisiae.
Nucleic acids research - 1 Apr 2001
Donahue S L, Corner B E, Bordone L, Campbell C
Abstract excerpt
The Saccharomyces cerevisiae CDC9 gene encodes a DNA ligase protein that is targeted to both the nucleus and the mitochondria. While nuclear Cdc9p is known to play an essential role in nuclear DNA replication and repair, its role in mitochondrial DNA dynamics has not been defined. It is also unclear whether additional DNA ligase proteins are present in yeast mitochondria. To address these issues, mitochondrial...
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