Article
Canarypox virus expressing wild type p53 for gene therapy in murine tumors mutated in p53.
Cancer gene therapy - 1 Feb 2001
Odin L, Favrot M, Poujol D, Michot J P, Moingeon P, Tartaglia J, Puisieux I
Abstract excerpt
The antitumor activity of a recombinant canarypox virus expressing wild type murine p53 (ALVAC-p53) was investigated in two murine syngeneic tumors harboring an endogenous p53 mutation (CMS4 and TS/A). Direct intratumor injections of ALVAC-p53 in CMS4 pre-established subcutaneous tumors induced t...
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