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Article

Combination of p53 cancer vaccine with chemotherapy in patients with extensive stage small cell lung cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Feb 2006

Antonia Scott J, Mirza Noweeda, Fricke Ingo, Chiappori Alberto, Thompson Patricia, Williams Nicholas, Bepler Gerold, Simon George, Janssen William, Lee Ji-Hyun, Menander Kerstin, Chada Sunil, Gabrilovich Dmitry I

Abstract excerpt

PURPOSE: The initial goal of this study was to test the immunologic and clinical effects of a new cancer vaccine consisting of dendritic cells (DC) transduced with the full-length wild-type p53 gene delivered via an adenoviral vector in patients with extensive stage small cell lung cancer. EXPERIMENTAL DESIGN: Twenty-nine patients with extensive stage small cell lung cancer were vaccinated repeatedly at 2-week...

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PMID: 16467102
DOI: 10.1158/1078-0432.CCR-05-2013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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