Article
A new algorithm for analysis of within-host HIV-1 evolution.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2001
Ren F, Ogishima S, Tanaka H
Abstract excerpt
A new algorithm for inferring the evolution of within-host viral sequences is presented. A sequential-linking approach is developed so that a longitudinal phylogenetic tree can be reconstructed from sequential molecular data that are obtained at different time points from the same host. The algorithm employs a codon-based model, which uses a Markov process to describe substitutions between codons, to calculate...
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