Article
Serial evolutionary networks of within-patient HIV-1 sequences reveal patterns of evolution of X4 strains.
BMC systems biology - 16 Jun 2009
Buendia Patricia, Narasimhan Giri
Abstract excerpt
BACKGROUND: The HIV virus is known for its ability to exploit numerous genetic and evolutionary mechanisms to ensure its proliferation, among them, high replication, mutation and recombination rates. Sliding MinPD, a recently introduced computational method 1, was used to investigate the patterns of evolution of serially-sampled HIV-1 sequence data from eight patients with a special focus on the emergence of X4...
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