Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The molecular clock of HIV-1 unveiled through analysis of a known transmission history.

Proceedings of the National Academy of Sciences of the United States of America - 14 Sept 1999

Leitner T, Albert J

Abstract excerpt

Detailed knowledge about the rate and mode of the genetic variation is vital for understanding how HIV-1 induces disease and develops resistance as well as for studies on the molecular epidemiology and origin of the virus. To unveil the molecular clock of HIV-1 we analyzed a unique set of viruses from a known transmission history with separation times between samples of up to 25 years. The env V3 and p17gag...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Transmission, Infectious
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Products, env

Share to Gene Products, gag

Share to Infectious Disease Transmission, Vertical

Share to Models, Genetic

Share to Time Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 10485898
DOI: 10.1073/pnas.96.19.10752
PMCID: PMC17955

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The molecular clock of HIV-1 unveiled through analysis of a known transmission history.PMID 10485898Read ↗

Tempo and mode of nucleotide substitutions in gag and env gene fragments in human immunodeficiency virus type 1 populations with a known transmission historySemantic proximity Read ↗

Molecular clock of HIV-1 envelope genes under early immune selection.Semantic proximity Read ↗

The Molecular Population Genetics of HIV-1 Group OSemantic proximity Read ↗

Factors influencing estimates of HIV-1 infection timing using BEAST.Semantic proximity Read ↗

Validation of molecular clock inferred HIV infection ages: evidence for accurate estimation of infection datesSemantic proximity Read ↗

Reconstructing the dynamics of HIV evolution within hosts from serial deep sequence data.Semantic proximity Read ↗

Evidence for a Recombinant Origin of HIV-1 group M from Genomic VariationSemantic proximity Read ↗

The Genealogical Population Dynamics of HIV-1 in a Large Transmission Chain: Bridging within and among Host Evolutionary RatesSemantic proximity Read ↗

Dating the common ancestor of SIVcpz and HIV-1 group M and the origin of HIV-1 subtypes using a new method to uncover clock-like molecular evolution.Semantic proximity Read ↗

Phylogenetic approach to recover integration dates of latent HIV sequences within-hostSemantic proximity Read ↗

Molecular clock-like evolution of human immunodeficiency virus type 1.Semantic proximity Read ↗

Evolutionary history of HIV-1 subtype B and F infections in Brazil.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.