Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dwarfism and early death in mice lacking C-type natriuretic peptide

20 Mar 2001

Abstract excerpt

Longitudinal bone growth is determined by endochondral ossification that occurs as chondrocytes in the cartilaginous growth plate undergo proliferation, hypertrophy, cell death, and osteoblastic replacement. The natriuretic peptide family consists of three structurally related endogenous ligands, atrial, brain, and C-type natriuretic peptides (ANP, BNP, and CNP), and is thought to be involved in a variety of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Connective tissue disorders research
Share to Neonatal Respiratory Health Research
Share to Pulmonary Hypertension Research and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11259675
DOI: 10.1073/pnas.071389098

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dwarfism and early death in mice lacking C-type natriuretic peptidePMID 11259675Read ↗

Significance of C-type natriuretic peptide (CNP) in endochondral ossification: analysis of CNP knockout mice.Semantic proximity Read ↗

Overexpression of CNP in chondrocytes rescues achondroplasia through a MAPK-dependent pathway.Semantic proximity Read ↗

Role of the natriuretic peptide system in normal growth and growth disorders.Semantic proximity Read ↗

Translational research of C-type natriuretic peptide (CNP) into skeletal dysplasias.Semantic proximity Read ↗

CNP, the Third Natriuretic Peptide: Its Biology and Significance to the Cardiovascular SystemSemantic proximity Read ↗

Systemic Administration of C-Type Natriuretic Peptide as a Novel Therapeutic Strategy for Skeletal DysplasiasSemantic proximity Read ↗

[Genetic basis for skeletal disease. CNP therapy for achondroplasia].Semantic proximity Read ↗

Mutations in C-natriuretic peptide (NPPC): a novel cause of autosomal dominant short stature.Semantic proximity Read ↗

The Local CNP/GC-B system in growth plate is responsible for physiological endochondral bone growth.Semantic proximity Read ↗

C-type natriuretic peptide and overgrowth.Semantic proximity Read ↗

Mesenchymal expression of activated K-ras yields Noonan Syndrome-like bone defects that are rescued by mid-gestational MEK inhibitionSemantic proximity Read ↗

A novel loss-of-function mutation in Npr2 clarifies primary role in female reproduction and reveals a potential therapy for acromesomelic dysplasia, Maroteaux type.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.