Article
Role of the natriuretic peptide system in normal growth and growth disorders.
Hormone research in paediatrics - 1 Jan 2014
Vasques Gabriela A, Arnhold Ivo J P, Jorge Alexander A L
Abstract excerpt
The C-type natriuretic peptide (CNP) and its receptor (NPR-B) are recognized as important regulators of longitudinal growth. Animal models involving CNP or NPR-B genes (Nppc or Npr2) support the fundamental role of CNP/NPR-B for endochondral ossification. Studies with these animals allow the deve...
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