Article
C-type natriuretic peptide and overgrowth.
Endocrine development - 1 Jan 2009
Bocciardi Renata, Ravazzolo Roberto
Abstract excerpt
Natriuretic peptides are a family of structurally related peptides with different distinct biological effects. C-type natriuretic peptide (CNP)-mediated signaling is important for endochondral ossification and intervenes in the control of chondrocyte maturation by regulating the balance between proliferation and terminal differentiation. CNP is encoded by the NPPC gene on human chromosome 2 for which, so far, no...
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