Article
NXT1 (p15) is a crucial cellular cofactor in TAP-dependent export of intron-containing RNA in mammalian cells.
Molecular and cellular biology - 1 Apr 2001
Guzik B W, Levesque L, Prasad S, Bor Y C, Black B E, Paschal B M, Rekosh D, Hammarskjöld M L
Abstract excerpt
TAP, the human homologue of the yeast protein Mex67p, has been proposed to serve a role in mRNA export in mammalian cells. We have examined the ability of TAP to mediate export of Rev response element (RRE)-containing human immunodeficiency virus (HIV) RNA, a well-characterized export substrate i...
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