Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nuclear Export of Human Hepatitis B Virus Core Protein and Pregenomic RNA Depends on the Cellular NXF1-p15 Machinery

31 Oct 2014

Abstract excerpt

Hepatitis B virus (HBV) core protein (HBc) can shuttle between nucleus and cytoplasm. Cytoplasm-predominant HBc is clinically associated with severe liver inflammation. Previously, we found that HBc arginine-rich domain (ARD) can associate with a host factor NXF1 (TAP) by coimmunoprecipitation. It is well known that NXF1-p15 heterodimer can serve as a major export receptor of nuclear mRNA as a ribonucleoprotein...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B Virus Studies
Share to RNA Interference and Gene Delivery
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25360769
DOI: 10.1371/journal.pone.0106683

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nuclear Export of Human Hepatitis B Virus Core Protein and Pregenomic RNA Depends on the Cellular NXF1-p15 MachineryPMID 25360769Read ↗

A Sub-Element in PRE enhances nuclear export of intronless mRNAs by recruiting the TREX complex via ZC3H18Semantic proximity Read ↗

Influenza polymerase encoding mRNAs utilize atypical mRNA nuclear exportSemantic proximity Read ↗

Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expressionSemantic proximity Read ↗

Hepatitis B virus Core protein nuclear interactome identifies SRSF10 as a host RNA-binding protein restricting HBV RNA productionSemantic proximity Read ↗

Viral Regulation of mRNA ExportSemantic proximity Read ↗

Nuclear Export and Import of Human Hepatitis B Virus Capsid Protein and ParticlesSemantic proximity Read ↗

Hepatitis B virus Core protein nuclear interactome identifies SRSF10 as a host RNA-binding protein restricting HBV RNA productionSemantic proximity Read ↗

NXT1 (p15) is a crucial cellular cofactor in TAP-dependent export of intron-containing RNA in mammalian cells.Semantic proximity Read ↗

The Ebola Virus Nucleoprotein Recruits the Nuclear RNA Export Factor NXF1 into Inclusion Bodies to Facilitate Viral Protein ExpressionSemantic proximity Read ↗

Modulation of HBV replication by microRNA-15b through targeting hepatocyte nuclear factor 1αSemantic proximity Read ↗

Recruitment of the Complete hTREX Complex Is Required for Kaposi's Sarcoma–Associated Herpesvirus Intronless mRNA Nuclear Export and Virus ReplicationSemantic proximity Read ↗

A long HBV transcript encoding pX is inefficiently exported from the nucleus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.