Article
Polymorphisms in the thrombopoietin gene are associated with risk of myocardial infarction at a young age.
Atherosclerosis - 15 Feb 2001
Webb K E, Martin J F, Hamsten A, Eriksson P, Iacoviello L, Gattone M, Donati M B, Di Castelnuovo A, Erusalimsky J, Humphries S E
Abstract excerpt
Five polymorphisms in the thrombopoietin (TPO) gene were identified, one in the 5' untranslated region (UTR) (C1796T), two within intron 5 (C4830A and A4877C), and two in the 3' UTR (A5713G and A6160T). The allele frequencies were determined in a group of 450 healthy middle aged men from the UK and found to be 0.46 for 1796T, 0.38 for 4830A, 0.004 for 4877C, 0.47 for 5713G and 0.07 for 6160T. Genotypes for the...
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