Prothrombin G20210A (rs1799963) polymorphism increases myocardial infarction risk in an age-related manner: A systematic review and meta-analysis.

doi:10.1038/s41598-017-13623-6

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Article

Prothrombin G20210A (rs1799963) polymorphism increases myocardial infarction risk in an age-related manner: A systematic review and meta-analysis.

Scientific reports - 19 Oct 2017

Li Changlong, Ren Hui, Chen Hong, Song Junxian, Li Sufang, Lee Chongyou, Liu Jun, Cui Yuxia

Abstract excerpt

G20210A polymorphism (rs1799963) within the prothrombin gene is associated with a higher circulation level of prothrombin, thus increasing the likelihood of developing myocardial infarction (MI). Opinions differ regarding the correlation between prothrombin G20210A genotype and MI risk, which prompted us to conduct a meta-analysis to determine this association. PubMed, EMBASE, Web of Science and CNKI were...

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PMID: 29051591
DOI: 10.1038/s41598-017-13623-6
PMCID: PMC5648836

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