Article
The effect of the C677T and A1298C polymorphisms in the methylenetetrahydrofolate reductase gene on homocysteine levels in elderly men and women from the British regional heart study.
Atherosclerosis - 15 Feb 2001
Dekou V, Whincup P, Papacosta O, Ebrahim S, Lennon L, Ueland P M, Refsum H, Humphries S E, Gudnason V
Abstract excerpt
Total blood levels of homocysteine (tHcy) have been shown to depend on both environmental and genetic factors, and to be associated with the risk of developing atherosclerosis with its complications of coronary heart disease (CHD) and stroke. In this study, 408 men and 346 women from two towns, Dewsbury and Maidstone were examined for tHcy levels and genotyped for the C677T and the A1298C polymorphisms in the...
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