Article
Gene-environment and gene-gene interaction in the determination of plasma homocysteine levels in healthy middle-aged men.
Thrombosis and haemostasis - 1 Jan 2001
Dekou V, Gudnason V, Hawe E, Miller G J, Stansbie D, Humphries S E
Abstract excerpt
Healthy middle-aged men (n = 1,470) from eight general practices across Britain were examined for plasma total homocysteine levels and genotyped for the A222V polymorphism in the methylene-tetrahydrofolate (MTHFR) gene, the 68 bp insertion polymorphism in exon 8 of the cystathionine b synthase (CBS) gene and the D919G polymorphism in the methionine synthase (MS) gene. The median value for plasma homocysteine was...
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