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Article

Role of ATP-Binding-Cassette Transporter Genes in High-Frequency Acquisition of Resistance to Azole Antifungals in <i>Candida glabrata</i>

1 Apr 2001

Abstract excerpt

Candida glabrata has been often isolated from AIDS patients with oropharyngeal candidiasis treated with azole antifungal agents, especially fluconazole. We recently showed that the ATP-binding-cassette (ABC) transporter gene CgCDR1 was upregulated in C. glabrata clinical isolates resistant to azole antifungal agents (D. Sanglard, F. Ischer, D. Calabrese, P. A. Majcherczyk, and J. Bille, Antimicrob. Agents...

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Share to Antibiotic Resistance in Bacteria
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PMID: 11257032
DOI: 10.1128/aac.45.4.1174-1183.2001

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