Article
The alpha 2-adrenergic receptor gene and body fat content and distribution: the HERITAGE Family Study.
Molecular medicine (Cambridge, Mass.) - 1 Feb 2002
Garenc Christophe, Pérusse Louis, Chagnon Yvon C, Rankinen Tuomo, Gagnon Jacques, Borecki Ingrid B, Leon Arthur S, Skinner James S, Wilmore Jack H, Rao D C, Bouchard Claude
Abstract excerpt
BACKGROUND: Among adrenergic receptor subtypes that regulate lipid mobilization, the alpha2-adrenergic receptor is involved in the inhibition of fatty acid mobilization from adipose tissue. A C-1291G polymorphism is located in the alpha2-adrenergic receptor gene (ADRA2A) but no association with body fat accumulation has been reported yet. MATERIALS AND METHODS: Body mass index (BMI), fat mass (FAT), percentage...
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