Article
Lack of evidence to support the association of the human prion gene with schizophrenia.
Molecular psychiatry - 1 Jan 2001
Tsai M T, Su Y C, Chen Y H, Chen C H
Abstract excerpt
Recently a new variant of Creutzfeldt-Jakob disease, a human prion disease, with prominent psychiatric manifestations in the early stage was identified, suggesting that human prion disease may be associated with mental disorders. Furthermore, a novel missense mutation with asparagine-to-serine substitution at codon 171 of the human prion gene (N171S) was identified in a family with severe psychiatric symptoms....
Topics
- Creutzfeldt-Jakob Syndrome
- Family Health
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Middle Aged
- Polymorphism, Genetic
- Prions
- Schizophrenia
- Taiwan