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Article

Lack of association between 14-3-3 beta gene (YWHAB) polymorphisms and sporadic Creutzfeldt-Jakob disease (CJD).

Molecular biology reports - 1 Dec 2012

Jeong Byung-Hoon, Jin Hyoung-Tae, Choi Eun-Kyoung, Carp Richard I, Kim Yong-Sun

Abstract excerpt

14-3-3 proteins are highly abundant in brain tissue. The presence of 14-3-3 at elevated levels in the cerebrospinal fluid has been considered as a biomarker for sporadic Creutzfeldt-Jakob disease (CJD). Recent studies showed that 14-3-3 beta protein interacts with the N-terminal amino acids 1-38 and with the central hydrophobic amino acids 106-126 of prion protein. This interaction may indicate a role of 14-3-3...

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Source

Identifiers

PMID: 23053962
DOI: 10.1007/s11033-012-1954-8

Genes

YWHAB

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Lack of association between 14-3-3 beta gene (YWHAB) polymorphisms and sporadic Creutzfeldt-Jakob disease (CJD).PMID 23053962Read ↗

A polymorphism in the YWHAH gene encoding 14-3-3 eta that is not associated with sporadic Creutzfeldt-Jakob disease (CJD).Semantic proximity Read ↗

Sensitivity of 14-3-3 protein test varies in subtypes of sporadic Creutzfeldt-Jakob disease.Semantic proximity Read ↗

14-3-3 CSF levels in sporadic Creutzfeldt-Jakob disease differ across molecular subtypes.Semantic proximity Read ↗

PRNP 1368 polymorphism is not associated with sporadic Creutzfeldt-Jakob disease in the Korean population.Semantic proximity Read ↗

RARB and STMN2 polymorphisms are not associated with sporadic Creutzfeldt-Jakob disease (CJD) in the Korean population.Semantic proximity Read ↗

Detection of 14-3-3 protein in the cerebrospinal fluid supports the diagnosis of Creutzfeldt-Jakob disease.Semantic proximity Read ↗

Polymorphisms at codons 56 and 174 of the prion-like protein gene (PRND) are not associated with sporadic Creutzfeldt-Jakob disease.Semantic proximity Read ↗

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Cerebrospinal fluid markers in sporadic Creutzfeldt-Jakob disease.Semantic proximity Read ↗

Current clinical diagnosis in Creutzfeldt-Jakob disease: identification of uncommon variants.Semantic proximity Read ↗

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Use of 14-3-3 in the diagnosis of Creutzfeldt-Jakob disease.Semantic proximity Read ↗

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