Article
No association between the brain-derived neurotrophic factor gene and schizophrenia in a Japanese population.
Schizophrenia research - 1 May 2006
Watanabe Yuichiro, Muratake Tatsuyuki, Kaneko Naoshi, Nunokawa Ayako, Someya Toshiyuki
Abstract excerpt
Brain-derived neurotrophic factor (BDNF) plays important roles in the survival, maintenance and growth of neurons. Several studies have indicated that BDNF is likely to be related to the pathogenesis of schizophrenia. Recent genetic analyses have revealed that BDNF gene polymorphisms are associated with schizophrenia, although contradictory negative findings have also been reported. To assess whether three BDNF...
Topics
- Adult
- Asian People
- Brain-Derived Neurotrophic Factor
- Case-Control Studies
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Haplotypes
- Humans
- Male
- Polymorphism, Single Nucleotide
- Schizophrenia
