Article
PRNP 1368 polymorphism is not associated with sporadic Creutzfeldt-Jakob disease in the Korean population.
European journal of neurology - 1 Aug 2008
Jeong B-H, Lee K-H, Lee Y-J, Kim Y-H, Cho Y-S, Carp R I, Kim Y-S
Abstract excerpt
BACKGROUND: Human prion protein gene (PRNP) is considered a critical and fundamental gene in determining the incidence of human prion diseases. Codons 129 and 219 play an important role in the susceptibility to sporadic Creutzfeldt-Jakob disease (CJD). An association between sporadic CJD and the polymorphism (PRNP 1368) in an upstream of PRNP exon 1 has been reported in the British and German populations, but...
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