Article
Modeling genetic architecture: a multilinear theory of gene interaction.
Theoretical population biology - 1 Feb 2001
Hansen T F, Wagner G P
Abstract excerpt
The map from genotype to phenotype is an exceedingly complex function of central importance in biology. In this work we derive and analyze a mathematically tractable model of the genotype-phenotype map that allows for any order of gene interaction. By assuming that the alterations of the effect of a gene substitution due to changes in the genetic background can be described as a linear transformation, we show...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
