Article
Tissue factor is not involved in the mitogenic activity of factor VIIa.
Biochemical and biophysical research communications - 1 Mar 2001
Herbert J M, de Prost D, Ollivier V, Melis E, Carmeliet P
Abstract excerpt
The present study was undertaken to evaluate in vitro the importance of tissue factor in the mitogenic effect of factor VIIa for embryonic fibroblasts. For that purpose, embryonic fibroblasts were isolated from either wild-type or transgenic mice showing a single inactivation of the tissue factor...
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