Article
Memory phenotype CD8(+) T cells in IL-15 transgenic mice are involved in early protection against a primary infection with Listeria monocytogenes.
European journal of immunology - 1 Mar 2001
Yajima T, Nishimura H, Ishimitsu R, Yamamura K, Watase T, Busch D H, Pamer E G, Kuwano H, Yoshikai Y
Abstract excerpt
We recently constructed IL-15 transgenic (Tg) mice using cDNA encoding a secretable isoform of the IL-15 precursor protein under the control of an MHC class I promoter. The IL-15 Tg mice exhibited resistance against a primary infection with Listeria monocytogenes. The numbers of memory CD8(+) T c...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.