Article
Compromised generation of GABAergic interneurons in the brains of Vax1-/- mice.
Development (Cambridge, England) - 1 Sept 2004
Taglialatela Paola, Soria José Miguel, Caironi Veronica, Moiana Alessia, Bertuzzi Stefano
Abstract excerpt
The subcortical telencephalon is the major source of GABAergic interneurons that, during development, tangentially migrate to the cerebral cortex, where they modulate the glutamatergic excitatory action of pyramidal cells. The transcription factor Vax1, an intracellular mediator of both Shh and F...
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