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Article

Neutrophil specific granule deficiency and mutations in the gene encoding transcription factor C/EBP(epsilon).

Current opinion in hematology - 1 Jan 2002

Gombart Adrian F, Koeffler H Phillip

Abstract excerpt

Neutrophil specific granule deficiency (SGD) is a rare congenital disorder. The neutrophils of these patients display atypical bilobed nuclei; lack expression of at least one primary and all secondary and tertiary granule proteins; and possess defects in chemotaxis, disaggregation, receptor upregulation, and bactericidal activity. SGD patients suffer frequent and severe bacterial infections. Although the first of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11753076
DOI: 10.1097/00062752-200201000-00007

Genes

EBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Neutrophil specific granule deficiency and mutations in the gene encoding transcription factor C/EBP(epsilon).PMID 11753076Read ↗

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