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Article

Dosage suppressors of pds1 implicate ubiquitin-associated domains in checkpoint control.

Molecular and cellular biology - 1 Mar 2001

Clarke D J, Mondesert G, Segal M, Bertolaet B L, Jensen S, Wolff M, Henze M, Reed S I

Abstract excerpt

In budding yeast, anaphase initiation is controlled by ubiquitin-dependent degradation of Pds1p. Analysis of pds1 mutants implicated Pds1p in the DNA damage, spindle assembly, and S-phase checkpoints. Though some components of these pathways are known, others remain to be identified. Moreover, the essential function of Pds1p, independent of its role in checkpoint control, has not been elucidated. To identify loci...

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Identifiers

PMID: 11238935
DOI: 10.1128/MCB.21.6.1997-2007.2001
PMCID: PMC86795

Genes

DDI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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