Article
UBA domains mediate protein-protein interactions between two DNA damage-inducible proteins.
Journal of molecular biology - 9 Nov 2001
Bertolaet B L, Clarke D J, Wolff M, Watson M H, Henze M, Divita G, Reed S I
Abstract excerpt
The Saccharomyces cerevisiae genes RAD23 and DDI1 were identified in a screen for multicopy suppressors of the temperature-sensitivity of a mutant allele of S. cerevisiae PDS1. Pds1 is a regulator of anaphase that needs to accumulate and then be degraded by the ubiquitin-proteasome pathway at the metaphase-anaphase transition for cells to progress normally through mitosis. Both the Rad23 and Ddi1 pds1 suppression...
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