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Article

Regulation of the urokinase-type plasminogen activator receptor gene in different grades of human glioma cell lines.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Feb 2001

Bhattacharya A, Lakka S S, Mohanam S, Boyd D, Rao J S

Abstract excerpt

We reported previously that the production of urokinase-type plasminogen activator receptor (uPAR) protein is greater in high-grade glioblastomas than in low-grade gliomas. Transcriptional activation of the uPAR gene or increased stability of the uPAR mRNA that encodes this protein could cause the increased production of this protein in cell lines of different grades of gliomas. We found similar half-life of uPAR...

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PMID: 11234878

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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