Article

Overexpression of CIRP in astrocytes contributes to Alzheimer’s disease via downregulation of uPA

2024-07-30

Abstract excerpt

<title>Abstract</title> <p>Background: Cold inducible RNA-binding protein (CIRP) is an important danger-associated molecular pattern involved in tissue-specific and systemic inflammation and is also regarded as a potential regulator of Alzheimer’s disease (AD). However, the precise roles and mechanism of CIRP in the functional changes in astrocytes during the development of AD are still unknown. This study aimed...

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Literature Corpus work: 52f88412-def4-5ce0-941c-8c77c597337e
DOI: 10.21203/rs.3.rs-4685039/v1

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