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Article

Gender influences herpes simplex virus type 1 infection in normal and gamma interferon-mutant mice.

Journal of virology - 1 Mar 2001

Han X, Lundberg P, Tanamachi B, Openshaw H, Longmate J, Cantin E

Abstract excerpt

Gender influences the incidence and severity of some bacterial and viral infections and autoimmune diseases in animal models and humans. To determine a gender-based difference, comparisons were made between male and female mice inoculated with herpes simplex virus type 1 (HSV-1) by the corneal route. Mortality was higher in the male mice of the three strains tested: 129/Sv//Ev wild type, gamma interferon...

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Identifiers

PMID: 11222734
DOI: 10.1128/JVI.75.6.3048-3052.2001
PMCID: PMC115935

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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