Article
Differentiation of Ly49s-positive or -negative natural killer cells is inhibited by anti-H-2b monoclonal antibodies acting at the level of bone marrow progenitors from B6 mice.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Jan 2001
Delfino D V, Salcedo M, Marco B D, Ayroldi E, Nocentini G, Bruscoli S, Brunetti L, Ljunggren H G, Riccardi C
Abstract excerpt
To investigate the role of MHC class I on in vitro differentiation of natural killer (NK) cells, a CD44low/-CD2-classlow population was isolated from mouse bone marrow. This population, which lacked expression of NK-1.1, Ly49A, Ly49C/I, and Ly49G, generated populations of NK-1.1+ NK cells expressing Ly49A, Ly49C/I, or Ly49G when cocultured for 13 days with syngeneic supportive stromal cells in the presence of...
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