Article
Use of stem cell radiation chimeras to analyze how domains of specific proteins impact on murine NK cell development in vivo.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010
Lian Rebecca H, Kumar Vinay
Abstract excerpt
Although the use of mutant mice has been extremely useful in identifying those proteins and molecules specifically required for the development of NK cells, the establishment of a well-defined protocol to replicate in vitro the major steps corresponding to the process of NK cell differentiation and maturation has enabled us to dissect the molecular events governing certain aspects of NK cell development. This...
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