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Article

Thrifty genotypes and phenotypes in the pathogenesis of type 2 diabetes mellitus.

Journal of pediatric endocrinology & metabolism : JPEM - 1 Jan 2000

Ong K K, Dunger D B

Abstract excerpt

Dramatically high rates of type 2 diabetes mellitus (DM) have been observed in historically undernourished, recently urbanized populations. A comparable model is the high risk of DM in individuals who were growth restrained in utero and subsequently catch up in size. While it is proposed that undernutrition may somehow adversely program metabolism, both models could also be explained by genotypes that promoted...

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Identifiers

PMID: 11202218
DOI: 10.1515/jpem-2000-s616

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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