Article
Genetic basis, nutritional challenges and adaptive responses in the prenatal origin of obesity and type-2 diabetes.
Current diabetes reviews - 1 Mar 2012
Gonzalez-Bulnes Antonio, Ovilo Cristina
Abstract excerpt
Obesity and type-2 diabetes are currently considered global pandemics. A large set of epidemiological evidences are addressing both the importance of a genetic predisposition -starting with the thrifty genotype hypothesis- and the determinant role of the maternal nutrition during pregnancy -starting with longitudinal studies of individuals born during the Dutch famine- on the adult onset of the disease....
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