Article
Insights from the developing world: thrifty genotypes and thrifty phenotypes.
The Proceedings of the Nutrition Society - 1 May 2005
Prentice Andrew M, Rayco-Solon Pura, Moore Sophie E
Abstract excerpt
Few researchers would dispute that the pandemic of obesity is caused by a profound mismatch between humanity's present environmental circumstances and those that have moulded evolutionary selection. This concept was first articulated when gestational diabetes was described as being the result of a 'thrifty genotype rendered detrimental by progress'. More recently, this hypothesis has been extended to the concept...
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