Article
A bi-allelic VNTR in the human TNFR2 (p75) gene promoter.
Genes and immunity - 1 Nov 1999
Keen L, Wood N, Olomolaiye O, Bidwell J
Abstract excerpt
We describe a bi-allelic VNTR polymorphism within a 42 bp region in the promoter of the tumour necrosis factor receptor 2 gene (TNFR2). Within this region there are one (Allele 1) or two (Allele 2) repeats of a 15 bp sequence, 5'-GCCGGGC AGGTGGAG-3'. Allele frequencies observed in a Caucasian population were 0.3 (Allele 1) and 0.7 (Allele 2).
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