Article
Resistance to fusidic acid.
International journal of antimicrobial agents - 1 Aug 1999
Turnidge J, Collignon P
Abstract excerpt
Resistance to fusidic acid is determined by a number of mechanisms. The best described are alterations in elongation factor G, which appear in natural mutants that are harboured at low rates in normal populations of staphylococci (10(6) to 10(8)). Altered drug permeability has also been described, and appears to be plasmid-borne. Binding by chloramphenicol acetyltransferase type I and efflux are other described...
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