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Article

Analysis of the human tumour necrosis factor-alpha (TNFα) gene promoter polymorphisms in children with bone cancer

1 Oct 2000

Abstract excerpt

Editor—TNFα (tumour necrosis factor-alpha) is a cytokine produced by macrophages and monocytes with a wide range of activities, and polymorphisms within this gene have been postulated to contribute to MHC associations with autoimmune and infectious diseases.1 The role of TNFα in cancer is a controversial matter, because while it plays a key role in the “in vitro” killing of tumour cells by macrophages and...

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PMID: 11183184
DOI: 10.1136/jmg.37.10.789

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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