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Article

Role of tumour necrosis factor gene polymorphisms (-308 and -238) in breast cancer susceptibility and severity.

Breast cancer research : BCR - 1 Jan 2004

Azmy Iman A F, Balasubramanian Saba P, Wilson Anthony G, Stephenson Timothy J, Cox Angela, Brown Nicola J, Reed Malcolm W R

Abstract excerpt

INTRODUCTION: Genetic polymorphisms in the promoter region of the tumour necrosis factor (TNF) gene can regulate gene expression and have been associated with inflammatory and malignant conditions. We have investigated two polymorphisms in the promoter of the TNF gene (-308 G>A and -238 G>A) for their role in breast cancer susceptibility and severity by means of an allelic association study. METHODS: Using a...

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Identifiers

PMID: 15217507
DOI: 10.1186/bcr802
PMCID: PMC468647

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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