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Article

EGF family ligand-dependent phenotypic modulation of smooth muscle cells through EGF receptor.

Biochemical and biophysical research communications - 23 Feb 2001

Yamanaka Y, Hayashi K, Komurasaki T, Morimoto S, Ogihara T, Sobue K

Abstract excerpt

The phenotypic modulation of smooth muscle cells (SMCs) is closely associated with the development and progression of various SMC diseases. We investigated the molecular mechanism of phenotypic modulation triggered by EGF family ligands using a primary culture system of differentiated SMCs. Among four EGF-receptor (EGFR) family members, the EGFR was solely activated by EGF, heparin-binding EGF (HB-EGF),...

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Source

Identifiers

PMID: 11181057
DOI: 10.1006/bbrc.2001.4385

Genes

EGF
EGFR
BTC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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